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Types and quality requirements of tablets produced by tablet presses
Release time:
2013-04-18 16:53
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Types and quality requirements of tablets produced by tablet presses
Types: ordinary compressed tablets, coated tablets, sugar-coated tablets, film-coated tablets, enteric-coated tablets, effervescent tablets, chewable tablets, multi-layer tablets, dispersible tablets, sublingual tablets, buccal tablets, implant tablets, solution tablets, sustained-release tablets Traditional Chinese medicine tablets refer to tablets or special-shaped tablets prepared by compressing fine powder of medicinal materials or extracts of medicinal materials with fine powder of medicinal materials or auxiliary materials. It is divided into raw powder tablets and extract (semi-extract) tablets.
Tablets during production and storage shall comply with the following
Relevant provisions:
1. raw materials and excipients should be mixed evenly. For tablets containing small doses or toxic dramatic drugs, the drug can be dispersed evenly by a suitable method according to the nature of the drug.
2. all volatile or thermally decomposed drugs, heat loss should be avoided during the tableting process. The granules should be controlled moisture to meet the needs of the tableting process and to prevent the tablets from becoming moldy, deteriorated and ineffective during storage.
3. drugs with unpleasant odor and taste, irritation, easy deliquescence or deterioration in light can be sugar-coated or film-coated after being made into tablets. For some gastric juice easily damaged, stimulate the gastric mucosa or need to be released in the intestine of the drug, tablets should be coated with enteric coating. In order to meet the needs of vaginal topical use, can be made into vaginal tablets. Some drugs can also be made into effervescent tablets as needed.
The appearance of 4. tablets should be complete and smooth, with uniform color; it should have appropriate hardness to avoid fragmentation during packaging, storage and transportation.
5. Unless otherwise specified, tablets shall be stored sealed.
Commonly used fillers include starches, sugars, celluloses and inorganic salts. Determined by tableting process, preparation equipment and other factors, the diameter of tablets should generally not be less than 6mm and the weight of tablets should be more than 100mg. If the main drug in tablets is only a few milligrams or tens of milligrams, tablets cannot be made without adding appropriate fillers. Therefore, thinner here has played a more important role in increasing the volume to help its molding.
Key words:
Laboratory Equipment
Packaging Equipment
pharmaceutical equipment
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